Regidor worked in the colonial government including posts of Secretary of the High
Court of Manila and President of Public Instruction.
In 1868, Regidor returned from studies in Spain to work in the Spanish colonial government.
During his term as Chief Inspector of Municipal Schools, he secured the royal decree
that allowed Filipinos from any social status to enter in public schools.
After the Cavite Mutiny, the Spanish authorities arrested anyone they suspected as
instigators and supporters, Regidor, a known Filipino sympathizer, was implicated
in the mutiny. As a result, he was arrested and sentenced to eight years of exile
in the Marianas Islands.
Regidor escaped from Guam and in April 1876, presented himself to the Spanish Consul
in Paris and was pardoned. He left Paris and resided in London, where he set up a
law office that served as overseas correspondent for Spanish publications. He wrote
articles for the propaganda newspaper La Solidaridad.